Commercial MLS Listings

One seller is a licensed Missouri Realtor.

Prime location with nearly 100 feet of Highway 61 frontage. Water, sewer, and electric are available. It is surveyed and ready for you to bring your business to the hi...

Fully operated and open business! This restaurant offers a friendly & relaxed dining experience. Owner Operated. Located in the downtown area and is considered one of ...

Unlimited usage on this 15 +/- Commercial Development Property. Located alongside I-55 and just at the Cape SportsPlex makes the location highly desirable. This booming ...

REMARKABLE piece of history preserved and now FOR SALE! The WM Brooks property dates back to 1840-1850 and is a profitable store and Airbnb in the heart of the National P...

None

None

None

66x115 Commercial Lot.

A completely remodeled fully furnished office building ready to move into is rare to find in Cape Girardeau! From the roof to the floor, this 8200 square foot office buil...

Versatile 11,000 square ft. commercial building in Doniphan. A great multi use business ready for a church, daycare, or recreational center. The building is designed for ...

2.59 acres & shop buildings just outside Cape city limits. 5768 sq ft building consisting of 3000 sq ft shop with additional office area & 1200 sq ft barn area. 1200 sq...

Trailer park for sale with 6.4 acres just outside city limits. Property consists of mobile homes, mini storage & shop buildings, county water and wells. Plenty of room ...

This building presents lots of opportunities- this can be store-fronted into several retail or service areas, it can be utilized as is for a medical or dental professiona...

Beautifully updated church building located in Jackson just off E. Jackson Blvd. near Hope St./Hwy 61. This 3,620 SF building is zoned R-2, but currently suitable for ch...

Are you looking for a place for your business or a commercial rental opportunity? Located in a high traffic area on North Chamber Drive, this six office unit rental boast...

Move in ready commercial office space completely remodeled in 2014. Private offices, large conference room, and ADA compliant entrance and bathroom. High traffic frontage...

Medical Office Building For Sale $1,150,000 Asking Price 18,207 SF 1.30 Ac

This is an outstanding business opportunity! Jeremiah's has a 35+ history of providing outstanding food and service to the Sikeston area. This is a profitable, successf...

Located in a high traffic area in Ste. Genevieve is this commercial building awaiting its new owners. This building was formally used as a restaurant, but has endless pos...

This 9398 square foot building is commonly known as the Medical Arts Building and has hosted many Doctors over the years. It sets in a PRIME LOCATION just South of Missou...

Endless possibilities with this property. This portion has been completely renovated with 4 half baths, 1 full bath with shower, 1 separate shower room, prep room, severa...

Endless possibilities with this property. This portion is a wide open unfinished space. Some possible options would be storage units or warehouse space for a growing busi...

Great location for new or existing business. Zoned M-1 Light manufacturing. 9,400 sq ft. Upper mezzanines for additional storage-3,364 sq ft. Large office area & show...

$175,900 422 W. Pine St Poplar Bluff MO 63901 Commercial building with 7,611 SF so space galore in this one! Building has had some updates & good condition on the inter...

$125,000 705-709 N. 9th St. Poplar Bluff MO 63901 Commercial building with 4,000 SF that is currently split in to 3 separate suites. Units are in good condition, with u...

Commercially zoned house in historic, downtown Farmington. Could make a great AirBnB, office space, store, etc. Brand new Hvac system, roof, and vinyl siding. Freshly pr...

Premier location anchored by national retailer Orscheln. If you can dream it, you can do it here! Centrally located in the heart of Dexter's business district, this 10,70...

This commercial listing on 2200 South Westwood Blvd boasts impressive attributes. With its prime southwest location, it offers great curb appeal and abundant natural ligh...

2,546 SF medical office building with multiple entrances and great off-street paved parking. Building can be configured for one or two businesses.

Located in a medical/office complex with interstate visibility is this 9,857 SF office building. Building includes multiple offices, exam rooms, and both private and publ...

Looking to own your own business this could be it! Auto parts store has been in business for over 50 years. Owner is ready to retire. This is a great opportunity with a w...

Introducing an incredible opportunity for entrepreneurs and investors alike! This newly built 2022 retail building has endless potential offering a modern and inviting d...

Fully Operational Huddle House, sit down restaurant, located on high traffic corner in central Cape Girardeau. Built in 2007 with an additional dining room added later fo...

Welcome to this rare find in Jackson. This 6-plex features 6 units each with 2 bedrooms/2 baths, open floor plan with vaulted ceilings, all appliances including washer a...

This commercial property (3.95 acres) is located close to Shelby Road off of Business 67. There are 3 parcels offered with this listing. Two residential rental properti...

None

8238 Hwy M Poplar Bluff, MO 63901; $450,000: Fully functioning convenience store operating as " The Little Store." Fully remodeled kitchen and pizza shop offering daily h...

$750,000 9376 State Hwy 21S Doniphan MO. Operating as Doniphan Liquor Store, this is a fully functioning convenience store with 2 brand new fuel pumps & newer above grou...

1.76-acre lot with shop, greenhouses, and outbuilding. Well, septic, and electric on-site. Property is located in a floodplain.

Great office with a 2nd level lot in the rear which goes all the way to the electric pole. 1 car detached garage. Kitchen with cooktop and garbage disposal in 2015, refri...

Large mix use commercial building sitting on 2.07 +/- acres. This property is sitting in a high traffic area and has 490+ ft of highway frontage. 1 acre of the property i...

ATTENTION ANTIQUE LOVERS!! Check out this 100’x100’ store FULL of beautiful furniture, gorgeous glassware and some really neat off-the-wall items that are a MUST SEE! Thi...

Land and Buildings for SALE! This property and buildings will make a great Business investment for someone! Land is 1.15 acres with no city code restrictions or permits n...

Discover the ideal business environment at 1925 William, Cape Girardeau. This commercial office building offers contemporary spaces designed to elevate your professional ...

None

Are you an investor looking to add to your rental portfolio or someone looking for some garage space for personal use? Take a look at this garage building with four overh...

FOR SALE - The Riverhouse, A Wine Place! This picturesque wine bar and restaurant, complete with patio seating and open air pavilion, sits just 200 feet from the Mighty ...

Turn-Key bar or bar and restaurant - fully renovated and spotless! New egress entry added. Buy the building and take over the business known as 21 Taps. Tap line and bar ...

Seven lots priced as one!! Lots are level & offer frontage on 3 different streets adding value & potential use. All public utilities available including water, sewer, ele...

Location is everything for this new listing! Don't pass up this SWEET opportunity! Perryville's "Cone or Cup" is located on a corner lot, which fronts on Kingshighway, wi...

Turn key business opportunity for sale in Poplar Bluff. This business established and centrally located. 4800 sq ft building on 0.41 acres. Great visibility and easy acc...

GREAT LOCATION FOR COMMERCIAL REDEVELOPMENT! Surrounded by professional offices, churches, and banks, this PRIME parcel will make a perfect location for a custom professi...

Commercial Building previously used as a Convenience store could now have many uses! Retail Store/ Hair or Nail Salon/ C-Store/ Laundry Mat/ Detail Shop etc. There i...

Located on bustling Broadway Street, this commercial building has endless possibilities! The main level features a display window, inviting gathering space, kitchenette, ...

Come with an open mind and see all that could be! 309 W First St consists of 2 separate buildings, 1 two story home split, can be renovated into 4 different 1 bedroom uni...

20 storage units - fully rented plus 4 acres for room to build more units. Also, 4800 sq ft building currently operating as a restaurant, however, could be converted to c...

Welcome to Villa 18/Suite 17, located in the stunning Chaumette Winery in the heart of Missouri Wine Country. This 4 bed, 4 bath villa/suite comes fully furnished, with m...

***TURNKEY BUSINESS OPPORTUNITY*** Just a little over 30 minutes from St Louis, on outer road of Interstate 70 with a daily traffic count of 26,800 vehicles per day you h...

This turn-of-the-century Downtown building has endless possibilities. Located on a corner lot with high traffic counts, the all brick building can house 3 separate busine...

Pick your acre(s). Seller will sell one (or more) acres of this PRIME Commercial Property with Highway 160 frontage at Doniphan. Property sits between Current River Ford ...

PRIME 6.8 acres of Commercial Property with 600 feet of Highway 160 frontage at Doniphan. Property sits between Current River Ford and Harp's Supermarket. Fantastic acces...

None

None

HIGHLY MOTIVATED SELLER! PRICE REDUCED! Potential Investment: Options for this building are endless. the original building was built for a hospital in 1932. In 1973 addit...

13,694 SF, single level commercial building with multiple entrances from 3 separate streets, Main, Independence and Water Streets. Large open areas and office areas that ...

This commercial building has so much to offer. The potential is endless! There is a store front window, a show room, storage rooms, an apartment, plus an oversized gara...

Two industrial buildings on 8.26 acres of property. The buildings are 6,000 SF and 4,800 SF, each with a drive-in door and loading dock. They also include an office are...

This beautiful property in Downtown Cape Girardeau is a gem, with exceptional views of the Mighty Mississippi to the rich history dating back to 1925. Originally the Cape...

For sale or lease with option to purchase- 2940 SqFT building- this building has a storefront- display area. A large showroom has the capability to add an overhead door. ...

$89,900. 1517 Grove, Poplar Bluff, MO 63901. 32x24 Mutli-Use Commercial Building. metal roof, Office, Retail Store Front, Property runs from Grove To Harper Street. 50x12...

Great Commercial Opportunity with this renovated 8,000' former Dollar General building with heat & air and 2 restrooms with maintenance rooms and overstock area concrete...

Prime Real Estate in Kennett, Mo. 12,060 Sq. Ft. Metal Building on 2 Acres, m/l. Located on the South By Pass, just off the corner of State Hwy 412 and Hwy VV. Close to t...

$399,000 715 Specialty Dr. Dexter MO Check out this fantastic commercial office opportunity in central Dexter business district!! This "like new" 2 story brick building...

INTRODUCING A RARE OPPORTUNITY TO OWN A TURN-KEY, PREMIER EVENT RENTAL VENUE * Known as “THE FRONT PORCH”, this sparkling gem is superbly designed & equipped to host a va...

Here's a rare opportunity to own a move-in ready commercial space on one of the busiest intersections in Malden, MO. Boasting a recent interior remodel, open concept flow...

Prime Development Commercial Lots: Offering 278’ M/L State Highway 412 frontage. There are 2 tracks, Track 1 is104’ x 256.4’ and Track 2 is 173.5’ x 140’. City utilities ...

1135 Lester Street, Poplar Bluff, MO - Approx. 12,000 sq ft of mixed-use office, retail and warehousing space centrally located in a high traffic corridor. The main level...

BEAUTIFUL 3,200 SQ. FT. COMMERCIAL BUILDING IN FREDERICKTOWN: Located in a high traffic area on Lincoln Dr., this 3,200 sq. ft. building offers 4 overhead doors, office ...

Fantastic opportunity to own this beautiful commercial property on Union Street! This property could be leased out as two storefronts with over 2,000 sq ft each, could co...

Fully Operational Septic System Business with on site living quarters and additional rural acreage. This is a turn-key operation as Business is being sold with all equipm...

Outstanding Renovated (2017) Office Building For Sale! Conveniently located in a high traffic area on Business 60 and very close to US 60, soon to be I-57. Amenities i...

15 acre mobile home park with 7 total units. 4 are currently rented with rent range from 500 to 675 per month. Plenty of room for growth and possible RV park. Schedule a ...

Property was a fully working veterinary office with a surgical site, until recently. The property includes all equipment used in the day-to-day workings of the office as ...

This concrete block building is bordered on north boundary by asphalt-surfaced Grant Street, on the west side by asphalt surfaced Catalpa Street, on the east by a Townhou...

This 7,000 sf building is a prime real estate opportunity that combines a superb location, versatile space, & a secure investment. This property presents an enticing oppo...

Professional Service Building available, fully occupied. Two units rehabbed in the last 2 years. High traffic area. Easy access and great exposure for your business!

None

Great investment opportunity located conveniently on PP Hwy property has very high traffic volume. This 2.66 Acre m/l property offers an 1800 sq ft residential home along...

Check out this great semi-level commercial lot that I think you should check out. It's located in a high-traffic area, so you'll get a lot of exposure for your business. ...

None

Located in the heart of Cape Girardeau overlooking the Arena Bldg. Property consist of 3 units: 2720 sq ft, 2688 st ft & 880 sq ft. Roof appx 10 yrs old, 2 meters, separ...

Potential abounds in this 3200 sq. ft. building that was last used as a church! This spacious building had a frozen water pipe last winter that busted and flooded the fl...

This historic 1925 Craftsman style bungalow commercial building is completely gutted down to the bare bones. Some of the electrical work has been started. You can make ...

This historic restaurant, bar and hotel- Audubon's, built in 1903, its located in the newly designated, Ste Genevieve National Historic Park. A turnkey opportunity in the...

.76 acres of Commercial C2 zoning. City will allow a portable building to be used for business for 1 year, while you build permanent structure. Any business you see on Bu...

his property is a perfect spot for a new private or franchise Business. Large meeting venue with warehouse area and large parking lot. A 7500 square foot rental building ...

Great Business opportunity, this steel building has 15,000 square feet with 2- 9ft. high overhead doors and 1- 10 ft. high door . Perfect loading dock size with concrete ...

Unique opportunity with this listing located in Kennett!! This is a turnkey church ready for new owners! This building has plenty of space. Located inside you will find a...

Business opportunity knocks!! This your chance to own a successful B-B-Q business in Doniphan, Mo. Located on U.S. Hwy 160E, in one of the busiest location in town. This ...